Cambridge Urology Partnership

Kidney, Bladder & Ureters

Kidney Cancer

Kidney cancer starts in the tubes that filter your blood. Often found by chance during scans, it is highly treatable if caught early. Modern treatments now focus on removing only the tumour to save as much healthy kidney tissue as possible.

Key Takeaways

  • Kidney cancer starts in the tubes that filter your blood. Often found by chance during scans, it is highly treatable if caught early. Modern treatments now focus on removing only the tumour to save as much healthy kidney tissue as possible.
  • We offer specialist diagnostics and treatments. Book a consultation to discuss your options.

Clinical Overview

Understanding Kidney Cancer

Kidney cancer, most commonly called Renal Cell Carcinoma (RCC), begins in the lining of the tiny tubes inside your kidney. These tubes are responsible for filtering your blood and turning waste into urine. Many cases are discovered "incidentally"—this means they are found by surprise during an ultrasound or CT scan for something else, often before you even feel unwell.

Because your kidneys have a very rich blood supply, tumours can sometimes grow quite large before they cause any pain or change how your body functions. There are different types of kidney cancer, such as "clear cell" or "papillary," and each type reacts differently to modern treatments.

In the UK, the focus of treatment has shifted towards "Nephron-Sparing Surgery." In the past, the whole kidney was often removed. Now, urologists use robotic-assisted "keyhole" surgery to remove only the tumour (Partial Nephrectomy) where possible. This leaves the healthy part of your kidney behind, which helps protect your long-term health and reduces the risk of kidney disease later in life.

What to Look For

Symptoms, Causes & Risk Factors

Recognising early signs and understanding the underlying causes of your condition is the first step toward recovery. This guide outlines common symptoms, when to seek specialist advice, and the factors that may influence your health.

01

Common Symptoms

  • Blood in your pee: This might look bright red or rusty/dark.

  • A dull ache or constant pain: Usually felt in your "flank" (the area between your ribs and your hip).

  • A lump or swelling: Feeling a mass in your side or abdominal area.

  • Losing your appetite: Often leading to unexplained weight loss.

  • Feeling very tired: This can be due to anaemia (a low red blood cell count).

  • Fever and sweats: High temperatures or drenching night sweats that aren't caused by a cold or flu.

02

When to Seek Help

  • Blood in your pee: Even if it only happens once and goes away.

  • A persistent pain in your side: Especially if it wasn't caused by an injury.

  • A new lump: Any unusual swelling in your tummy or side.

  • Sudden high blood pressure: If your blood pressure becomes very high or difficult to control.

  • Swollen ankles or legs: This can sometimes be a sign that the kidneys are under pressure.

03

Potential Causes

  • Genetic changes: Random mutations that happen as we age.

  • Inherited conditions: Around 5–8% of cases are linked to family genes, such as Von Hippel-Lindau (VHL) syndrome.

  • Environmental factors: Long-term exposure to certain chemicals or toxins.

  • Cellular signals: Abnormal protein signals in the body that tell cells to keep dividing.

04

Risk Factors

  • Smoke: Tobacco use is a major risk factor. The risk does go down after you quit, though it takes several years to return to normal.

  • Obesity: Being significantly overweight changes hormone levels that can trigger cell growth.

  • Have high blood pressure: Hypertension is a risk factor for kidney tumours.

  • Have long-term kidney issues: People on long-term dialysis have a higher risk of developing cysts and tumours.

  • Workplace history: Past exposure to substances like cadmium, asbestos, or certain industrial cleaning chemicals.

  • Gender: In the UK, men are about twice as likely as women to be diagnosed.

Importance of Diagnosis

Why Early Diagnosis Matters

Finding kidney cancer early is the single most important factor for a successful recovery. If the tumour is small and still contained within the kidney (Stage 1), the survival rate in the UK is over 90%. Many patients are completely cured just by having the tumour removed.

If diagnosis is delayed, the cancer can grow into the large veins near the kidney or spread to the lungs and bones. Kidney cancer doesn't usually respond well to traditional chemotherapy, so catching it early enough for surgery or for modern "targeted" therapies is vital for the best long-term outcome.

Living With Condition

Living With Kidney Cancer

  • Robotic Partial Nephrectomy
  • Radical Nephrectomy
  • Ablation
  • Active Surveillance
  • Immunotherapy & Targeted Therapy

Living with kidney cancer often starts with "Active Surveillance." If a tumour is very small (under 3cm) and slow-growing, especially in older patients, your doctor might suggest monitoring it with regular scans rather than rushing into surgery. This avoids the side effects of an operation unless the tumour shows signs of growth.

If you have had surgery, looking after your remaining kidney tissue is your top priority. This usually involves a "kidney-friendly" lifestyle: keeping your salt and protein intake at a moderate level, staying well-hydrated, and making sure your blood pressure and blood sugar are strictly managed.

For those whose cancer has returned or spread, modern "Immuno-Oncology" is often effective. These treatments help your own immune system to recognise and kill cancer cells. Compared to older treatments, these modern combinations offer a much better quality of life and allow many people to live well with the condition for a long time.

Specialists

Our specialists for Kidney Cancer

Leading experts for this condition. View profiles to see clinical backgrounds and current availability.

Our Commitment

Care you can trust

Every step of your care is delivered to the same standard: senior consultants, a personalised plan, and the safety of an accredited private hospital behind you.

Consultant-Led Excellence

Receive evidence-based care delivered by senior NHS consultants in a professional, specialist setting.

Personalised Care Plans

Your consultant will design a bespoke plan tailored to your condition, health goals and lifestyle.

Hospital-Grade Safety

We operate within leading private hospitals, adhering to strict CQC safety and technology standards.

A Heritage of Trust

Our partners bring decades of NHS and private experience, successfully managing thousands of patient cases.

Patient Guidance

Frequently Asked Questions

Common questions about specialist referrals and consultations.

3 questions

Generally, no. A single healthy kidney is more than capable of filtering the blood for the entire body. Most people who undergo a radical nephrectomy (full removal) lead normal lives with normal kidney function. However, we monitor your renal function closely post-surgery and advise a healthy diet and blood pressure management to protect the remaining kidney.

Reviewed 2 Mar 2026

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A Small Renal Mass (SRM) is a tumor typically less than 4cm. Not all of these are cancerous, and many that are cancer are slow-growing. In older patients or those with other health issues, we often use 'Active Surveillance' (regular scans) rather than immediate surgery. For younger, fit patients, we typically recommend a robotic partial nephrectomy to remove the mass while it is small.

Reviewed 2 Mar 2026

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Unlike other cancers, we rarely biopsy a kidney mass first. A high-quality CT or MRI scan is often so accurate at identifying the characteristics of kidney cancer that urologists can plan the treatment based on the imaging alone. We typically reserve biopsies for specific cases where the diagnosis is very unclear or teh results will change treatment decisions.

Reviewed 2 Mar 2026

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